Chronological events of scientific exploration (Neurohumoral transmission)
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Lewandousky (1899)
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Administered extracts of the adrenal glands pointed towards the concept of chemical transmission
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Elliott (1904-05)
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Worked out similarities between stimulation of sympathetic nerves, administration of adrenal extracts and epinephrine
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Dixon (1907)
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Similarity between muscarine alkaloids and vagal stimulation
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Sir Henry Dale (1914)
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Similarities between choline esters and Ach coined "muscarinic and nicotinic"
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Otto Loewi (1920)
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Obtained first real proof of chemical neurotransmissions
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Noble Laureates
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Dale (1936)
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Fundamental contributions to concept of chemical Neurotransmission
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Loewi (1936)
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First proof of chemical neurotransmission
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Eccles (1963)
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Major electrophysiological contributions to nerve transmission
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Axelrod (1970)
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Established the major ways of inactivation of catecholamines
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Von Euler ( 1970)
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Established norepinephrine as neurotransmitter of adrenergic nerves
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Katz (1970)
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Important electrophysiological observations and concept of quantal release
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Sutherland (1972)
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Co-discoverer of cyclic AMP
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Black (1988)
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β-blockers
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Gilman (1994)
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G-proteins
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Rodbel (1994)
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G-proteins
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Furchgott (1998)
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Nitric Oxide
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Murad (1998)
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Nitric Oxide
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Ignarro (1998)
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Nitric Oxide
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Carlsson (2000)
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CNS neurotransmission
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Greengard (2000)
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CNS neurotransmission
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Kandel (2000)
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CNS neurotransmission
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Last modified: Tuesday, 15 May 2012, 5:02 AM
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