Neuropharmacology: Catecholamine

Catecholamine - Isoprenaline

ISOPRENALINE

Isoprenaline (Isoproterenol/Isopropylarterenol)

It is a direct acting synthetic catecholamine which predominantly stimulatesβ1 and β2 receptors. Its main actions are seen on the heart, blood vessels of skeletal muscles and smooth muscles of bronchi and GI tract.
Isoprenaline decreases the peripheral resistance and increased blood flow to skeletal muscles, with little effect on cutaneous, mucosal and renal blood vessels. Overall, it lowers the blood pressure.
On the heart, isoprenaline has positive inotropic and positive chronotropic effects with increased COP and in this respect it is more potent than adrenaline and noradrenaline.
Isoprenaline relaxes all smooth muscles. Metabolic effects are similar to adrenaline

Last modified: Monday, 23 May 2011, 5:30 PM

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VPT 321: Veterinary Neuropharmacology (2+1)

Catecholamine - Isoprenaline

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