Physical factors
Irradiation
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Irradiation produces interference with spermatogenesis by injuring spermatogonia, spermatocytes and spermatids.
The spermatocytes are most sensitive to irradiation while leydig and sertoli cells are quit resistant.
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Steroidogenesis is not affected much by the X-rays. The testosterone level is maintained as such.
Hyperthermia
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The causes for the elevation of testicular temperature are cryptorchid and ectopic testes, inguinal hernia, scrotal dermatitis due to irritants, chorioptic mange, myiasis in sheep and localized skin infections or wounds, contusions and haematomas of the scrotum and testes, prolonged body temperature as in certain infectious diseases and in prolonged high environmental temperature particularly associated with high humidity.
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Males that are unable to rise, often develops testicular degeneration and atrophy due to the prolonged elevation of testicular temperature from the testes being held close to the body.
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The temperature more than 410C has detrimental effect on spermatogenesis.
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The cells undergoing meiosis are more sensitive than resting sperm but there is no change in steroidogenesis.
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Late pachytene primary spermatocytes and early round spermatids are more sensitive.
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Hypothermia
Light
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The influence of light on control of spermatogenesis is brought through the capacity of it to control the pituitary gonadotrophin.
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The pineal body operated as a neuroendocrine transducer mediating light effects on the testes.
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The shortened photoperiod (below 12 hrs) decrease the capacity of the pituitary to release of gonadotrophin, possibly by reducing sensitivity to gonadal steroid hormone feedback. Thereby it brings about effect on spermatogenesis.
Low oxygen tension
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Last modified: Monday, 11 June 2012, 11:04 AM