Veterinary Clinical Medicine-II

REPLACEMENT THERAPY

• 50 % glucose 500ml I/V, 20 % glucose I/P,
• Propylene glycol or glycerine @ 225 mg / day for 2 days then 110 mg / day for 2 days.
• In sheep, common complication is acidosis. So sodium bicarbonate is to be given along with replacement therapy.
• Sodium propionate 110 -225 mg/ day, but shows very slow response.
• Lactates: Ca or sodium lactate 1 kg initially, later ½ kg / day for 7 days or
• Sodium acetate 110-500 g/day.
• Ammonium lactate 200g/day for 5 days.
• Ewes: Sodium ethyl oxaloacetae I/V (costly).
• Anabolic steroids: Effective treatment for pregnancy toxemia of cows. Trenbolone acetate @ 60mg to 100 mg as single injection.
• Insulin with glucose or glucocorticoids 200 – 300 I.U. Repeat every 24 – 48 hrs. There is no marked therapeutic advantage.