Clinico pathological changes in hypomagnesemic tetany

CLINICO PATHOLOGICAL CHANGES IN HYPOMAGNESEMIC TETANY

Clinical pathology

  • In clinical cases- serum Mg level will be from 0.3 to 0.7 mg%. (Normal: 1.7 to 3 mg.)
  • Estimation of Ca:Mg ratio in bone. Normal is 70:1, If Ca <70 – safe , >70 – problem Eg. 90:1 could be taken as a severe case.
  • Serum creatinine phosphokinase increased.
  • SGOT increased (marginally).
  • Decreased levels of CSF Mg (sample can be collected upto 12 hrs after death). Normal being 2 mg%.  i.e similar to plasma level.  In clinical cases: 1.25 mg%
  • There may be clinically normal cows with hypomagnesaemia (0.4 mg% - 1.84 mg%)
  • Low Urine Mg is a good presumptive evidence.

Postmortem examination

  • Extravasation of blood in subcutaneous area, endocardium, pleura, peritoneum and intestinal mucosa.
Last modified: Thursday, 19 May 2011, 5:27 AM