Systematic Veterinary Bacteriology and Mycology

DIAGNOSIS, CONTROL AND PREVENTION

• Based on history, symptoms and characteristic lesions strongly suggestive of this disease.
• FAT is to be employed for differentiate it from C.chauvoei .
• Identification of specific clostridial toxin by mixing 1.2ml of culture fluid with 0.3ml of specific antitoxin, allowing the mixture to stand for 30 minutes at 37⁰C and inoculate two guinea pigs intra peritoneally. If specific toxin present it will be neutralized.
• Penicillin alone or with hyper immune serum can be used to treat infections.
• Sheep can be effectively immunized against the disease and multi component vaccine is used.