Veterinary Preventive Medicine-II

PREVENTION AND CONTROL

• There is no treatment for PPR.
• Oxytetracycline and chlortetracycline are recommended to prevent secondary bacterial infections.
• Hyper immune serum which may be obtained from cattle hyper immunized against rinderpest can be used as therapy.
• Quarantine of the newly purchased animals, isolation of the affected animals, and following strict hygienic measures will helps to control the disease.

Vaccines

• Sheep or goats vaccinated with PPR vaccine at the age of 6 months and booster dose should be given once in a year.
  • The tissue culture rinderpest vaccine at a dose of 10^2.5 TCID50 protects goats for atleast 12 months against PPR.
  • The vaccine is currently used in many African countries for vaccination against PPR. This vaccine is safe in pregnant goats.
  • A homologus PPR tissue culture vaccine produced by attenuation in vero cells is commercially available.
  • In southern India, a homologus PPR vaccine using AR-87 strain is used to control PPR in sheep and goats.
  • This vaccine was developed at the Department of Veterinary Microbiology, Madras Veterinary College.
  • Newly developed recombinant vaccinia or capripox viruses expressing the fusion (F) and Haemagglutinin (H) protein genes of the rinderpest virus are also effective against PPR.