Corticotropin Releasing Hormone (CRH)
|
|
|
CRH (CORTICOTROPIN RELEASING HORMONE)
|
-
It is a 41 amino acid peptide that stimulates ACTH synthesis and release by the corticotroph cells of pituitary gland.
-
Stress enhances its synthesis and release. CRH secretion is influenced by circadian light- darkness cycle.
-
In diurnal animals (cattle, dog, horse) it stimulates ACTH synthesis during morning hours.
-
Other functions of CRH include stimulating the sympathetic nervous system, decreasing elevated body temperature, and suppressing reproductive functions and sexual activities, suppressing GH release and altering behaviour.
|
Last modified: Thursday, 9 February 2012, 10:39 AM
Participants