Veterinary Clinical Medicine-I (General and Systemic)

PATHOGENESIS

Toxaemia and septicemia

• Toxins produced by bacteria are absorbed readily through the peritoneum. Toxaemia is important factor in the production of clinical illness

Acute diffuse peritonitis

• Toxaemia is profound
• Endotoxic shock due to absorption of toxins from the gut contents.
• Cows which suffer penetration of the reticular wall at calving

Shock and hemorrhage

• The shock  by sudden deposition of gut contents or infected uterine contents into the peritoneal cavity
• Hemorrhage resulting from the rupture are significant contributors

Abdominal Pain

• Animal adopts an arched back posture
• Shows evidence of pain on palpation of the abdominal wall.
• Humped up posture

Paralytic ileus

• Reflex inhibition of alimentary tract tone and movement.
• Sequel to intestinal obstruction and to traumatic abdominal surgery.
• The net effect is functional obstruction of the intestine and complete absence of feces.
• Accumulation of fluid exudates.

Adhesions

• Trauma results in serosanguineous exudates, which contain fibrinogen and plasminogen.
• Intraabdominal fibrin deposition and adhesion formations