Hormonal factors
Exogenous steroids
Small doses of testosterone may impair spermatogenesis to a greater degree than larger doses due to ability of the larger dose to maintain the seminiferous epithelium.
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In some species steroid suppression of testis has been followed by a rebound phenomenon after steroid withdrawal.
Pituitary factors
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Reduced spermatogenesis with testicular atrophy may be caused by failure of FSH and LH.
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Many stress factors affect LH and FSH release, the most important being inanition due to low plane of nutrition.
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Tumors of the pituitary gland also cause atrophy of the pituitary gland and failure of gonadotropic production.
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Last modified: Tuesday, 12 June 2012, 4:29 AM