Clinical Nutrition

Lesson 17: Diseases of the liver

Functions of the Liver

• Glycogenesis
• Gluconeogenesis
• Conversion of galcatose and fructose to glucose
• Forming many important compounds from intermediary compounds.
• Formation of lipoproteins, cholesterol
• Oxidation of fatty acids
• Formation of bile salts
• Lipogenesis
• Deamination, transamination
• Formation of plasma proteins
• Urea formation
• Synthesis of non essential amino acids and other important compounds.
• Storage of vitamins, iron etc.
• Formation of blood coagulation factors
• Detoxification of certain drugs
• Synthesis of acute phase proteins

• Glycogenesis is the process of glycogen synthesis, in which glucose molecules are added to chains of glycogen for storage.
• Gluconeogenesis is a metabolic pathway that results in the generation of glucose from non- carbohydrate carbon substrates such as lactate, glycerol, and glucogenic amino acids.
• Lipogenesis is the process by which acetyl-CoA is converted to fats.

• pathological changes

• Major Agents