Vitamin A Deficiency
Normal and Therapeutic Nutrition 3(2+1)
Vitamin A Deficiency
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Epidemiology:
Age:
- Rare in infancy
- Highly prevalent in preschool & school children (1-3 yrs)
Socioeconomic factors:
- Low-income group
- Nutritional deficient mothers
- Food fads and fallacies, eg. colostrum/papaya/green leafy vegetables are avoided
- Poor families cannot afford animal meat (rich in preformed vitamin A)
Aetiology:
- Inadequate dietary intake of vitamin A or its precursor (?-carotene)
- Vitamin A deficient diets consumed by pregnant and lactating women and off spring born with poor stores of vitamin A.
Symptoms:
Deficiency symptoms show up after the liver reserves of vitamin A has been depleted.
Symptoms may result from
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Low dietary intakes
Interference in absorption and storage
Interference in conversion of ?-carotene to vitamin A.
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Clinical signs:
- Night blindness
- Conjunctival Xerosis
- Bitot’s spot
- Corneal xerosis
- Corneal ulceration/keratomalacia
- Corneal scar
- Xerophthalmic fundus
- Increased susceptibility to infection
Treatment:
- Oral dose of vitamin A. Prophylactic dose of 2 lakh IU of vitamin A once in 6 months upto 6 years.
- Intramuscular injection
- Hospital admission if medical emergency
Prevention:
- Nutrition education
- Horticultural interventions including kitchen gardening
- Nutrient supplementation
- Prevention of infection
- Selective fortification
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Last modified: Monday, 24 October 2011, 9:04 AM