Normal and Therapeutic Nutrition

Normal and Therapeutic Nutrition 3(2+1)

Lesson 26:Cardiovascular and atherosclerosis – causes, symptoms

Atherosclerosis causative fatty acids

High intake of saturated fatty acid can lead to	Increased plasma --- Increased cholesterol atheroma formation. Increased LDL receptors --- Increased LDL cholesterol. Arrhythmia --- Thrombosis. Increased Lipid oxidation ---- Injury to coronary arteries. Increased factor VII level ---- Thrombosis. Decreased antiaggregatory prostacyclin. Decreased HDL cholesterol. Plasma triglycerides.
High cholesterol intake can lead to	Plasma cholesterol accumulation LDL synthesis LDL catabolism by cells.
Low ? – 3 fatty acids intake	Arrhythmia ----- Thrombosis Increased Fibrinogen ---- Thrombosis ---- Fibrous plaque Increased platelet aggregation --- Thrombosis. Increased lipoprotein (a) - Fibrous plaque Increased inflammation – injury to coronary arteries. B.P --- Injury to coronary arteries.

Table: Desirable cholesterol levels

Desirable cholesterol levels	mg/dl
Total cholesterol	< 200
HDL cholesterol	> 40
LDL cholesterol	< 150
VLDL cholesterol	< 40