Biotechnology and Bioinformatics (1+1)

1.1.2.7. Proteomics

The proteome is defined as the expressed protein complement of a cell, tissue, or whole organism. Proteomics was first used in 1994 by Williams and Hochstrasser. The proteome, unlike the genome, varies both temporally and between tissues as the fish grows and adapts its physiology to meet the demands of a new environment. As proteins are the final determinant of phenotype—the proteome that describes the abundance, identity, posttranslational modifications, and potentially the synthesis rates of proteins—an understanding of the regulation proteome is imperative to gain a holistic view of the animal. Proteomics use mass spectroscopy (MS) techniques to identify novel functional proteins from genes that are expressed.