Pathogenesis

PATHOGENESIS

  • Heavy infection occurs in young puppies below one year old. Smaller breeds are severely affected than larger breed.
  • Worms are attached to intestinal wall (mucosa) with the help of well-developed buccal capsule and suck the blood.
  • The worms frequently change the site of attachment. Hence numerous necrotic foci are seen. Since anticoagulants are found in the secretion of worms the blood continuously oozes from the site of attachment.
  • In heavy infection puppies becomes anaemic because each worms suck about 0.001 ml per day.
  • Development of anaemia  coincides with emerging L5 stage because it has developed buccal capsule (the anaemia is microcytic hypochromic).
  • In dogs due to skin penetration by L3 causes dermatitis and swelling of s/c tissue.
  • There will be decrease in RBC - Hb content and also haemorrhage in the lungs and pneumonia due to larval migration.
Last modified: Friday, 23 September 2011, 10:39 AM