Chemistry of cardiac glycosides

CHEMISTRY OF CARDIAC GLYCOSIDES

  • Cardiac are glycosides that contain an aglycone (genine) and a sugar moiety. (chemical structure picture hyper link)
  • The sugar moiety consists of one to four sugar residues.
  • The pharmacological activity rests with the aglycone and the sugar helps in the pharmacokinetic properties.
  • The aglycone consists of a cyclopentanoperhydrophenantherene ring structure attached to a 5 or 6 membered unsaturated lactone ring.
Last modified: Wednesday, 25 April 2012, 10:48 AM