VPT 321: Veterinary Neuropharmacology (2+1) copy 1

PHARMACOLOGICAL ACTIONS OF GANGLIONIC BLOCKERS

Organ	Predominant tone	Effects of ganglionic blockade
Cardiovascular	-	Overall depression
Arterioles	Sympathetic	Vasodilatation, increased peripheral blood flow, hypotension
Veins	Sympathetic	Vasodilatation, pooling of blood, decreased venous return
Heart	Parasympathetic	Tachycardia
Gastrointestinal tract	Parasympathetic	Decreased tone and motility, constipation
Eye	-	-
Iris	Parasympathetic	Mydriasis
Ciliary muscle	Parasympathetic	Cycloplegia
Urinary bladder	Parasympathetic	Urinary retention
Salivary glands	Parasympathetic	Dry mouth
Sweat glands	Sympathetic	Anhydrosis
Bronchioles	Parasympathetic	Relaxation, decreased secretion