VLD 421: Veterinary Clinical Biochemistry and Laboratory Diagnosis-II (0+1)

INTRODUCTION - HAEMAGGLUTINATION INHIBITION TEST

• The Haemagglutination Inhibition Test  is simple to perform and requires inexpensive equipment and reagents.
• It is a serological test.
• Serial dilutions of patient's sera are allowed to react with a fixed dose of viral haemagglutinin, followed by the addition of agglutinable erythrocytes.
• In the presence of antibody, the ability of the virus to agglutinate the erythrocytes is inhibited.
• Haemagglutination inhibition tests are widely used for the diagnosis of viral infections such as influenza, Newcastle disease etc.