Fish Diseases and Management

2.1.8 Inflammation in vertebrates

Inflamatory response occur following the release of pharmacodynamic amines (especially those found in mast cells histamine and 5-hydroxy tryptamine). They may be released by an agent capable of causing tissue damage, as almost all tissues have some component of mast cells. The most common causes of such  are microbes and their excretory products (toxins), physical and chemical trauma, death of cells from circulatory insufficiency and the immune reactions. White blood cells migrate through the fenestrae to the affected tissue. The degree of cellular migration depends to a considerable extent on the stimulus.

The cells which leave the blood include

1) Neutrophils (Polymorphonuclear leucocytes)

2) Monocytes or Mononuclear macrophages

3) Lymphocytes

4) Thrombocytes