Site pages
Current course
Participants
General
26 February - 4 March
5 March - 11 March
12 March - 18 March
19 March - 25 March
26 March - 1 April
2 April - 8 April
9 April - 15 April
16 April - 22 April
23 April - 29 April
30 April - 6 May
2.2.19 The Excretory system to be done
Kidney It has mainly three functions.
The basic functional unit of kidney is the nephron. Nephron is a tubular structure having a cup like Bowman’s capsule which contains glomerulus, which has coiled branched capillaries. Head kidney functions for haematopoiesis while mid kidney and posterior kidney are excretory in function . Pathology a) Glomerular nephritis Here the Bowman’s capsule becomes thickened leading to decrease in filtration efficiency of kidney. The epithelial layer will be sloughed off (detachment of epithelial layer) from the basement membrane and forms wide mass in the Bowman’s capsule which reduces the filtration efficiency. This may be happen due to some toxin produced by bacteria, virus and due to pollution. b) Parasitic deposition (Pathology) The pathology leads to deposition of glomerulus in the Bowman ’s capsule, which block the filtration capacity and finally damage the tissue. The parasitic deposition blocks the movement of the generated fluids in collecting ducts, etc. 2) Renal tubules Renal cell tubules get damaged causing tubular necrosis. This is due to antibiotics like erythromycin, sulphamerazine which cause kidney problem. a) Urolithiasis/Nephrocalcinosis Formation of calciated stones in nephrons, nephric duct etc. This happes due to high CO2 and a diet rich in calcium . c) Interstitial fibrosis This pathological change results due to proliferative kidney disease (PKDC). This may also be due to bacterial infection, leading to degradation of haemopoeitic tissue, haemopoeitic hyperplasia, vascular changes and diffused inflammation. d) Tumour generation Aflatoxin can generate tumour in liver. F. Nervous System The nervous system consist of brain, spinal cord, nerves and all other associated cell components. |