Lathyrogens

Food Standard and Quality Control

Lesson 16 : Food Toxicants

Lathyrogens

They are found in legumes such as chick peas and vetch, are hderivatives of amino acids that act as metabolic antagonists of glutamic acid, a neurotransmitter in the brain.

Excessive consumption of Lathyrus sativus leads to crippling, irreversible paralysis of both lower limbs, mainly in males. This is attributed to the presence of a non-protein amino acid, ?Noxalyl-L-2, 3-diaminopropionic acid or ?N-oxalylamino-L-alanine. Lathyrism is primarily a problem in some areas of India.

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Last modified: Saturday, 18 February 2012, 10:34 AM