Pathophysiology

PATHOPHYSIOLOGY
  • Acquired megacolon results from chronic retention of fecal material that leads to colonic absorption of fecal water and solidified fecal concretions.
  • Prolonged distension of the colon results in irreversible changes in colonic motility that leads to colonic inertia.
Last modified: Tuesday, 8 March 2011, 2:18 AM