Human Nutrition 3(3+0)

Lesson 11 : Digestion and Absorption of Fats

Digestion and Absorption of Lipids

Reactions in intestinal lumen	Reactions within intestinal wall	Mode of entry into circulation
a)Fat (Triglyceride) 3-10% absorbed Lipase as micelle Diglycerides + fatty acids 3-10% absorbed Lipase as micelle Monoglycerides + fatty acids 60-68% absorbed Lipase as micelle Glyerol + fatty acids 20% absorbed Phospholipids as micelle Phospholipids Glycerol + fatty acids + phosphoric acid + organic base (choline etc.) Absorption b) Cholesterol esters Cholesterol esterase Absorption Cholesterol + fatty acids c) Short chain fatty acids (C4 — C10 ) Absorption   d) Glycerol Absorption	Triglycerides and diglyerides are hydrolysed by intestinal lipase into monoglycerides and fatty acids. Resynthesis of neutral fat, phospholipids and formation of chylomicrons     Short chain fatty acids (C4 —C10 ) Glycerol	a)Through lymphatic vessels (lacteals) b)Triglycerides, cholesterol and Phospholipids in the form of chylomicrons
		Through portal blood a)Short chain fatty acids (C4-C10) b)Glycerol