Continuous cell lines

CONTINUOUS CELL LINES

  • These cells are capable of infinite number of divisions. Continuous cell lines arise from mutation in a cell strain or by establishment from malignant tissue.
  • The karyotype of these cells is aneuploid (variable multiple of haploid chromosome number)
  • These cell lines are morphologically different from the cells of origin and usually nutritionally less fastidious. Some cell lines are nonadherent and can grow in suspension. Continuous cell lines are useful in many viral studies. Eg: vero,BHK21 and HeLa
Last modified: Tuesday, 21 September 2010, 5:17 AM