Epidemiology and pathogenesis

EPIDEMIOLOGY AND PATHOGENESIS

Epidemiology of T. spiralis

  • There are two important cycles, which play a major role in the transmission of infection to the man.

Sylvatic cycle: (Wild animal)

  • In which carnivores like jackal and wild boars maintain the infection by cannibalism. Man may be infected by ingestion of wild animals meat.

Synanthropic zoonotic cycle: (Domestic animal)

  • Domestic animals are getting infection from wild animals due to close contact.

Pathogenesis

  • In domestic animals the infection cause no clinical signs, but in man the infection causes irritation and marked enteritis. The larva in the muscle fibre causing acute myositis, myocarditis, ascitis, periorbital oedema, eosinophlia and fever. In heavy infection death may occur due to paralysis of respiratory muscle.
Last modified: Tuesday, 17 April 2012, 5:33 AM