Introduction- Type III Hypersensitivity

INTRODUCTION- TYPE III HYPERSENSITIVITY

  • It is a type of antibody mediated hypersensitivity reaction characterized by
    • Deposition of antigen ( usually soluble antigen ) -antibody complex in the tissues (particularly on the vascular endothelial surface
    • Complement activation 
    • Massive infiltration of polymorphs, release of vasoactive molecules , inflammation and tissue destruction.
  • Two types of reactions are recognized
Last modified: Thursday, 26 August 2010, 9:34 AM