VMC 221: Veterinary Immunology and Serology (1+1)

SHORT THERMAL TEST

• Large volume of tuberculin solution is given subcutaneously and animal is examined for rise in temperature between 4 and 8 hours later (tuberculin acts on T cells that then release cytokines that stimulate macrophages to release IL-1).
• Used in post partum animals and infected animals.
• Advantage: High efficiency.
• Disadvantage: time consuming, may cause anaphylaxis