Significance
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- A normal ESR does not exclude the possibility of a disease process.
Increased ESR
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Acute general infections
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Increase in plasma fibrinogen by diets rich in proteins, in pregnancy and tissue inflammation and destruction
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Suppurative conditions
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Vascular malignant tumour with tissue break down
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Since equine blood normally shows increased rouleaxu formation, ESR reading is taken at 30 minutes
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ESR is specifically increased in diseases like distemper, leptospirosis, infectious canine hepatitis, filariasis, myocarditis, bacterial endocarditis, pleuritis, peritonitis, radiation injury, hypercholesterolaemia and chronic interstitial nephritis.
Decreased ESR
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Increase in the number of erythrocytes
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The presence of microcytes and poikilocytes
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Refrigerated temperatures
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Haemolytic jaundice
Diphasic sedimentation
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When reticulocytes, leptocytes, normoblasts and poikilocytes are present they settle at a slower rate while red cells settle faster. Due to this a trailing of RBC column is noticed in the tube. The line of separation of plasma and cell column is indistinct and a tail is noticed.
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Disphasic ESR is characteristically seen during response to immune mediated haemolytic anaemia and in erythrogenic alteration in active haemopoiesis.
Sample – No.
Result & Interpretation
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Last modified: Monday, 4 June 2012, 5:01 AM