VPT 421: Veterinary Toxicology (2+0)

TOXICITY

• Toxicity varies with the specific compound and route of administration involved.
• In general, introduction of an alpha - cyano moiety (type II pyrethroids) results in an increase in toxicity.
• Drugs, chemicals, nutritional changes that alters the effectiveness of the mixed function oxidase system can change the toxicity of the pyrethroids.
• Small animal poisoning occurs principally in cats.
• Rodents are also susceptible. Fish are often extremely sensitive.