Veterinary Preventive Medicine-II

CLINICAL MANIFESTATIONS

•  Incubation period is 3-8 days
• The disease may appear in three clinical forms
• Per acute form
  • Most commonly noticed in young pigs
  • Disease terminates fatally within about 24 hours of developing disease
  • No appreciable clinical manifestations except high raise of temperature and erythematous patches in the non-hairy parts of the skin
• Acute form
  • Sharp rise of body temperature. Temperature reaction may persist up to 8^th day or till death
  • Dullness, depression, anorexia, vomition, constipation, severe foul smelling diarrhoea, dehydration and loss of body weight
  • Hyperemia of the skin with purplish discoloration of snout, ears, abdomen, inner side of the legs, a peculiar blotching effect on the ears, small areas vesicular lesions followed by necrotic lesions on the edges of the ears, tail, lips and vulva
  • Mucopurulent to purulent discharges from eyes with signs of conjunctivitis
  • Severely affected pigs may suck urine and water due to obvious temperature reaction and dehydration
  • Central nervous system may be affected. The signs are wobbling gait, ataxia, tremor, convulsion, paralysis, circling, tremor and coma
  • Reproductive disorders in sows due to low virulent strain with signs of fever and birth of mummified, still birth, abnormal piglets
• Chronic form
  • Chronic diarrhea
  • Chronic pneumonia

Gross lesions

• Degeneration of small blood vessels leading to hemorrhages in kidney, bladder, skin and lymph nodes
• Circular or oval raised button ulcers are most prevalent in caecum and proximal portion of the colon

    

• Turkey egg appearance of kidney is the pathognomonic lesion of the disease.

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