Bio Chemistry

BIOCHEMISTRY 3(2+1)

Lesson 11 : Amino Acids – Classification, Properties and Peptide bonds

Acid-Base properties of Amino Acids

Titration curve for glycine

• Note that one starts with all groups in acid form.
• Note how many equivalents are added
• Note that at 0.5 and 1.5 equivalents, pH is equal to pK of group being titrated.
• Note pH which gives zero charge is the isoelectric point. Calculated as (pK1+ pK2)/2
• Note where the buffering capacity is best