Viral disease
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Histopathological changes
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IHHNV (Infectious hypodermal and hematopoietic necrosis virus) disease
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A prominent cowdry type A, eosinophilic intranuclear inclusion bodies (in haemotoxylin- eosin staining)within chromatin- marginated, hypertrophied nuclei of cells in tissues of ectodermal and mesodermal origin (hematopoietic organs, antennal gland, gonads, lymphoid organ, connective tissues and striated muscle)
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HPV (Hepatopancreatic parovirus) disease
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Lateral displacement and compression of the host cell nucleolus, which becomes hypertrophied and remains intimately associated with the developing inclusion body. In earlier infection, HPV inclusions are small eosinophilic bodies centrally located within the nucleus and closely associated with the nucleolus.
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BP (Baculovirus penaei) disease
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Polyhedral inclusion bodies (PIBs) in the target organ (hepatopancreas and anterior midgut), the virus causes striking cytopathological chages that include marked nuclear hypertrophy, chromatin diminution and margination, nucleolar dissociation in infected hepatopancreatic epithelial cells, and presence of a pronounced proliferation of the golgi to from a conspicuous membranous labyrinth.
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MBV (Monodon baculo virus) disease
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MBV occlusions apper as prominent, single or multiple, eosinophilic spherical bodies within the hypertrophied nuclei of hepatopancreatic tubule or midgut epithelial cells.
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WSSV (White spot syndrome virus) disease
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Prominent eosinophilic to pale basophilic inclusions in H and E stain.
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TSV(Taura syndrome virus) disease
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Necrosis in the cuticular epithelium of the general body surface, all appendages, gills, hindgut, esophagus, and stomach.
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YHV (Yellow head virus) disease
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Generally multifocal to diffuse severe necrosis, with prominent nuclear pyknosis and karyorrhexis. Basophilic, usually spherical, perinuclear cytoplasmic inclusions occur in affected tissues.
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