3.5.1.6 Oxidation of glyceraldehyde 3-phosphate to 1, 3 bisphosphoglycerate

3.5.1.6 Step 6: Oxidation of Glyceraldehyde 3-Phosphate to 1, 3 Bisphosphoglycerate

Glyceraldehyde-3-phosphate is converted to 1,3 bisphosphglycerate by glyceraldehyde 3-phosphate dehydrogenase using NAD+ as the coenzyme. Finally, by phosphorolysis, inorganic phosphate (pi) is added, forming1, 3 bisphosphoglycerate, and the free enzyme.

 Glyceraldehyde 3-hosphate dehydrogenase

Glyceraldehyde-3-phosphate + NAD1,3 bisphosphglycerate

+ NADH+ H+


Energy released during the oxidation is conserved by the formation of a high-energy sulfur group that becomes, after phosphorolysis, a high- energy phosphate group in position 1 of 1, 3 bisphosphoglycerate.
Last modified: Tuesday, 21 February 2012, 9:40 AM