Absorption and Fate

ABSORPTION AND FATE

  • Absorbed well from the gastrointestinal tract.
  • 96-99% of the absorbed fluoride is incorporated into hydroxyapatite crystalline structure of the bone.
  • Accumulation is proportional to the duration and rate of exposure.
  • Fluoride is depleted slowly from the bones.
  • Accumulation in skeleton is not of toxicological significance in foetal bone.
Last modified: Monday, 22 August 2011, 2:37 PM