VPT 421: Veterinary Toxicology (2+0)

Hyderogen Sulphide Poisoning

HYDROGEN SULPHIDE POISONING

• Hydrogen sulphide is released by the decomposition of sulphur compounds and is found in petroleum refineries, tanneries, mines and rayon industries.
• It is intensely toxic and relatively small amount are required to cause death.
• The gas may be formed from sulphur within the gut or from sulphate in the rumen.
• H ₂ S is said to inhibit enzyme systems concerned in cellular respiration and to paralyze the respiratory system.
• Symptoms are dyspnoea and cyanosis, decrease of reflex activity and convulsions.
• Post mortem findings include noncoagulation of the blood, endocardial and laryngeal hemorrhages, edema of lungs, toxic changes in the liver, kidney and spleen, hyperemia and edema of the digestive tract.
• Carbon dioxide may be a physiological antidote.
• Inhalation of a mixture of oxygen (90%) and CO ₂ (10%) may increase the tolerance of animals to H ₂ S.
• Adequate ventilation is necessary.