|
Course Introduction |
|
|
Syllabus |
|
|
11 March - 17 March |
Learning Objectives |
|
|
Toxicology - Definition |
|
|
Branches of Toxicology |
|
|
PODCAST |
|
|
18 March - 24 March |
Learning Objectives |
|
|
Major Disasters |
|
|
Scientists Associated with Toxicology |
|
|
Incidents of Importance in History of Toxicology |
|
|
Historical Developments |
|
|
PODCAST |
|
|
25 March - 31 March |
Learning Objectives |
|
|
Classification of Poisons |
|
|
Guidelines for the Cassification of Poisons Based on the Dose |
|
|
Acute Lethal Doses of Certain Compounds |
|
|
Symbolic Representation of Toxicity of Xenobiotics |
|
|
Types of Poisoning |
|
|
Toxicity Testing |
|
|
Chronicity Factor |
|
|
Untoward Effects due to Poisonous Substances |
|
|
Common Causes of Poisoning |
|
|
PODCAST |
|
|
1 April - 7 April |
Learning Objectives |
|
|
Introduction |
|
|
Historical Evidences |
|
|
Clinical Evidences |
|
|
Circumstantial Evidences |
|
|
Pathological Evidences |
|
|
Analytical Evidences |
|
|
Samples to be sent for Analytical Evidences |
|
|
PODCAST |
|
|
8 April - 14 April |
Learning Objectives |
|
|
Introduction |
|
|
Toxicant Disposition |
|
|
Absorption and Transport |
|
|
Tissue Distribution |
|
|
Biotransformation |
|
|
Excretion of Xenobiotics |
|
|
PODCAST |
|
|
15 April - 21 April |
Learning Objectives |
|
|
Toxicodynamics (Mechanism of Action) |
|
|
Specific Mechanisms of Intoxication |
|
|
Toxicokinetics and Toxciodynamics |
|
|
Stages of Toxicity Development |
|
|
Action at Delivery Stage |
|
|
Action After Interaction With Target Molecule |
|
|
Cellular Dysfunction and Injury |
|
|
Dysrepair |
|
|
PODCAST |
|
|
22 April - 28 April |
Learning Objectives |
|
|
Classification of Factors |
|
|
Toxicant Related Factors |
|
|
Exposure Related Factors |
|
|
Animal Related Factors |
|
|
Environment Related Factors |
|
|
PODCAST |
|
|
29 April - 5 May |
Learning Objectives |
|
|
Introduction |
|
|
Removal of the Source of the Poison |
|
|
Delaying Further Absorption with Emetics |
|
|
Gastric Lavage and Other Methods to Delay Absorption |
|
|
Hastening Elimination of the Absorbed Poison |
|
|
Supportive Therapy |
|
|
PODCAST |
|
|
6 May - 12 May |
Learning Objectives |
|
|
Antidotes |
|
|
Specific Antidotes |
|
|
Receptor Antagonists |
|
|
Alteration of Drug Metabolism |
|
|
Physiologic Antagonists |
|
|
Chelating Agents |
|
|
PODCAST |
|
|
13 May - 19 May |
Learning Objectives |
|
|
Characteristics of Toxic Metals |
|
|
Sources of Arsenic Poisoning |
|
|
Factors Affecting Toxicity |
|
|
Absorption and Fate |
|
|
Mechanism of Toxicity |
|
|
Consequences of Toxicity |
|
|
Clinical Symptoms |
|
|
PM lesions |
|
|
Diagnosis and Treatment |
|
|
PODCAST |
|
|
20 May - 26 May |
Learning Objectives |
|
|
Sources of Lead Poisoning |
|
|
Factors Influencing Toxicity |
|
|
Absorption and Fate |
|
|
Mechanism of Toxicity |
|
|
Clinical Symptoms |
|
|
PM Lesions |
|
|
Diagnosis |
|
|
Treatment |
|
|
PODCAST |
|
|
27 May - 2 June |
Learning Objectives |
|
|
Sources of Mercury Poisoning |
|
|
Absorption and Fate |
|
|
Mechanism of Toxicity |
|
|
Clinical Symptoms and PM Lesions |
|
|
Diagnosis and Treatment |
|
|
Sources of Iron Poisoning |
|
|
Properties of Toxicological Importance |
|
|
Absorption and Fate |
|
|
Mechanism of Toxicity |
|
|
Pathophysiology of Iron Toxicosis |
|
|
Clinical Symptoms and PM Lesions |
|
|
Treatment |
|
|
PODCAST |
|
|
3 June - 9 June |
Learning Objectives |
|
|
Sources of Selenium Poisoning (including plants) |
|
|
Absorption and Fate |
|
|
Mechanisms of Toxicity |
|
|
Clinical Symptoms and PM Lesions |
|
|
Diagnosis and Treatment |
|
|
PODCAST |
|
|
10 June - 16 June |
Learning Objectives |
|
|
Sources of Copper Poisoning |
|
|
Absorption and Fate |
|
|
Mechanism of Toxicity |
|
|
Clinical Symptoms and PM Lesions |
|
|
Treatment |
|
|
Sources of Molybdenum Poisoning |
|
|
Factors Affecting Toxicity |
|
|
Absorption and Fate |
|
|
Mechanism of Toxicity |
|
|
Clinical Symptoms |
|
|
Treatment |
|
|
PODCAST |
|
|
17 June - 23 June |
Learning Objectives |
|
|
Sources of Nitrite Poisoning |
|
|
Factors Affecting Toxicity |
|
|
Mechanism of Toxicity |
|
|
Clinical Symptoms and PM Lesions |
|
|
Diagnosis and Treatment |
|
|
Sources and Mechanism of Toxicity |
|
|
Clinical Symptoms, Diagnosis and Treatment |
|
|
PODCAST |
|
|
24 June - 30 June |
Learning Objectives |
|
|
Sources of Urea Poisoning |
|
|
Properties of Toxicological Importance |
|
|
Absorption and Fate |
|
|
Mechanism of Action |
|
|
Clinical Symptoms and PM Lesions |
|
|
Diagnosis and Treatment |
|
|
PODCAST |
|
|
1 July - 7 July |
Learning Objectives |
|
|
Sodium Chloride Poisoning (Salt Poisoning) |
|
|
Mechanism of Toxicity |
|
|
Clinical Symptoms and PM Lesions |
|
|
Diagnosis and Treatment |
|
|
Sources of Fluoride Poisoning (Fluorosis) |
|
|
Absorption and Fate |
|
|
Mechanism of Toxicity |
|
|
Clinical Symptoms and Treatment |
|
|
Carbon Monoxide Poisoning |
|
|
Sulphur Dioxide Poisoning |
|
|
Hyderogen Sulphide Poisoning |
|
|
Nitrogen Dioxide Poisoning |
|
|
PODCAST |
|
|
8 July - 14 July |
Learning Objectives |
|
|
Introduction |
|
|
Toxic Principles |
|
|
PODCAST |
|
|
15 July - 21 July |
Learning Objectives |
|
|
Atropa belladonna |
|
|
Conium maculatum (Hemlock) |
|
|
Datura stromonium (thorn apple, Jimson weed) |
|
|
Ipomoea species |
|
|
Nerium and Thevetia |
|
|
Solanum |
|
|
Strychnine |
|
|
PODCAST |
|
|
22 July - 28 July |
Learning Objectives |
|
|
Sources of Cyanide Poisoning |
|
|
Factors Affecting Toxicity |
|
|
Absorption and Fate |
|
|
Mechanism of Toxicity |
|
|
Clinical Symptoms and PM Lesions |
|
|
Diagnosis |
|
|
Treatment |
|
|
PODCAST |
|
|
29 July - 4 August |
Learning Objectives |
|
|
Oxalate containing plants |
|
|
Thiaminase containing plants |
|
|
Thiaminase Induced Toxicity |
|
|
Signs and treatment |
|
|
PODCAST |
|
|
5 August - 11 August |
Learning Objectives |
|
|
Cannabis sativa and Cannabis indica |
|
|
Milkweeds (Asclepias) |
|
|
Ricinus communis |
|
|
Abrus precatorius |
|
|
Allium species |
|
|
Calotropis gigantea |
|
|
Gossypium |
|
|
Lathyrus sativum |
|
|
PODCAST |
|
|
12 August - 18 August |
Learning Objectives |
|
|
Introduction |
|
|
Classification of photosensitization |
|
|
Primary Photosensitization or Type I |
|
|
Aberrant Endogenopus Pigment Synthesis or Type II |
|
|
Secondary (Hepatogenous) Photosensitization |
|
|
Type IV Photosensitivity |
|
|
Clinical Signs |
|
|
Diagnosis and Treatment |
|
|
Phenothiazine |
|
|
Absorption and Fate |
|
|
Clinical Signs |
|
|
Diagnosis and Treatment |
|
|
Tetradymia - Artemisia Poisoning |
|
|
Tribulus terrestris (Puncture vine) |
|
|
Lantana camara and Lippia spp. |
|
|
Lantana camara - Mechanism of Toxicity |
|
|
Parthenium |
|
|
PODCAST |
|
|
19 August - 25 August |
Learning Objectives |
|
|
Mycotoxin |
|
|
Aflatoxin Poisoning |
|
|
Properties of Toxicological Importance |
|
|
Toxicity |
|
|
Toxicokinetics |
|
|
Mechanism of Action |
|
|
Clinical Symptoms and PM Lesions |
|
|
Diagnosis and Treatment |
|
|
Rubratoxins |
|
|
Penicillic Acid |
|
|
PODCAST |
|
|
26 August - 1 September |
Learning Objectives |
|
|
Fumonisins |
|
|
Mechanisms of Action |
|
|
Clinical Symptoms |
|
|
PM Lesions, Diagnosis and Treatment |
|
|
Citreoviridin, Patulin and Ochratoxins |
|
|
Zearalenone |
|
|
PODCAST |
|
|
2 September - 8 September |
Learning Objectives |
|
|
Types of Bacterial Toxins |
|
|
Factors Causing Bacterial Growth in Foodstuff |
|
|
Toxicokinetics and Mechanism of Action of S. aureus and B. cereus |
|
|
Clinical Symptoms |
|
|
Treatment |
|
|
Botulism |
|
|
Mechanism of Action |
|
|
Clinical signs |
|
|
Treatment |
|
|
Tetanus |
|
|
Mechanism of toxicity |
|
|
Clinical Symptoms |
|
|
Treatment |
|
|
PODCAST |
|
|
9 September - 15 September |
Learning Objectives |
|
|
Introduction |
|
|
Organochlorine (Chlorinated hydrocarbon) |
|
|
Absorption and Fate |
|
|
Mechanism of Toxicity |
|
|
Clinical Symptoms and PM Lesions |
|
|
Diagnosis and Treatment |
|
|
PODCAST |
|
|
16 September - 22 September |
Learning Objectives |
|
|
Introduction |
|
|
Sources of Organophosphorus Compounds |
|
|
Properties of Toxicological Importance |
|
|
Mechanism of Action |
|
|
Mechanism of Toxicity |
|
|
Clinical Symptoms |
|
|
Treatment |
|
|
Introduction |
|
|
Toxicokinetics |
|
|
Mechanism of Action |
|
|
Clinical Symptoms and Treatment |
|
|
Differences between organophosphosphates and carbamates |
|
|
PODCAST |
|
|
23 September - 29 September |
Learning Objectives |
|
|
Sources of Pyrethrins and Pyrethroids |
|
|
Classification |
|
|
Toxicity |
|
|
Toxicokinetics |
|
|
Mechanism of Action |
|
|
Clinical Symptoms and PM Lesions |
|
|
Diagnosis and Treatment |
|
|
Rotenone |
|
|
Amitraz |
|
|
Ivermectin and Milbemycin |
|
|
PODCAST |
|
|
30 September - 6 October |
Learning Objectives |
|
|
Introduction |
|
|
Anticoagulant Rodenticieds |
|
|
Factors Enhancing Toxicity |
|
|
Toxicokinetics |
|
|
Mechanism of Toxicity |
|
|
Clinical Symptoms |
|
|
Diagnosis |
|
|
Treatment |
|
|
Alphanaphthyl Thiourea (ANTU) |
|
|
Bromethalin |
|
|
Cholecalciferol |
|
|
Phosphorus |
|
|
Red squill (Urginea maritima) |
|
|
Sodium fluroacetate |
|
|
Strychnine |
|
|
Thallium |
|
|
Zinc phosphide |
|
|
Metaldehyde |
|
|
Herbicides and Fungicides |
|
|
Avicides |
|
|
PODCAST |
|
|
7 October - 13 October |
Learning Objectives |
|
|
Zootoxins |
|
|
Snake poisoning |
|
|
Clinical signs, diagnosis, treatment |
|
|
Scorpion poisoning |
|
|
Spider poisoning |
|
|
Wasp sting |
|
|
Toad and poison arrow poisoning |
|
|
Avian poisoning |
|
|
Snail poisoning |
|
|
Fish Poisoning |
|
|
Tick Poisoning |
|
|
PODCAST |
|
|
14 October - 20 October |
Learning Objectives |
|
|
Introduction |
|
|
Hazard |
|
|
Risk |
|
|
Risk Assessment |
|
|
Risk Management |
|
|
Residue |
|
|
Importance of Residues |
|
|
Pharmacokinetics and Residues |
|
|
Safety of Veterinary Drugs |
|
|
Formation of Drug Residues |
|
|
Types of Residues |
|
|
Residues of Antibacterial Drugs |
|
|
Consumer Safety |
|
|
Acceptable Daily Intake |
|
|
Withdrawal Time |
|
|
MRL |
|
|
Prevention of Residues |
|
|
Control Systems for Residue Prevention |
|
|
Codex Alimentarius Commission and HACCP |
|
|
PODCAST |
|
|
21 October - 27 October |
Learning Objectives |
|
|
Introduction |
|
|
Historical Background |
|
|
UV Rays and Infrared Rays |
|
|
Radiation |
|
|
Radiation Source and Units |
|
|
Radioactive Material |
|
|
Irradiation- Sensitivity, Half life, Exposure, Absorption |
|
|
Industrial Toxicants |
|
|
Occupational Hazards |
|
|
PODCAST |
|
|
28 October - 3 November |
Learning Objectives |
|
|
Introduction |
|
|
Classes of Food Additives and Examples |
|
|
Toxicity of Feed Additives |
|
|
Safety of Feed Additives |
|
|
Reasons for Use of Feed Additives in Animal Feed |
|
|
Precautions to be Taken While Using Feed Additives in Animal Feed |
|
|
PODCAST |
|
|
4 November - 10 November |
Question Bank |
|
|
Reference and Further Reading |
|
|
Acknowledgement |
|