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4.3.6.Recombinant DNA-based vaccines
4.3.6.Recombinant DNA-based vaccines
Recombinant DNA technology has been widely used in development of novel vaccines that are now collectively termed as ‘recombinant DNA-based vaccines’ or ‘new gene ration vaccines’. Different types of vaccines based on recombinant DNA technology have been developed which include:
(i) recombinant immunogenic protein vaccines or epitopes purified from vector s carrying the gene of interest produced in prokaryotic or eukaryotic expression systems,
(ii) peptide vaccines,
(iii) live vaccines produced by defined genetic manipulations and microbial vectors carrying gene coding for immunogenic protein, and
(iv) Genetic vaccines (DNA vaccines and RNA vaccines)
(v) Subunit vaccine s.
Last modified: Thursday, 28 June 2012, 12:04 PM