Biotechnology and Bioinformatics (1+1)

4.3.11.1. RNA vaccines

Genetic vaccination through the delivery of RNA has also been investigated, but to lesser extent than DNA vaccination. RNA expression is short-lived, and is thus less effective in inducing an immune response. The preparation and administration of RNA is trouble some because of the low stability of the RNA. One advantage of the RNA strategy is that there is no risk of integration of the delivered gene into the host genome.