Biotechnology and Bioinformatics (1+1)

4.2.3 Gene chip or DNA microarray

A DNA microarray is a multiplex technology used in molecular biology . Microarray technology evolved from southern blot ting.

• Fragmented DNA is attached to a substrate and then probe d with a known gene or fragment.
• It consists of an arrayed series of thousands of microscopic spots of DNA oligonucleotide s , called features, each containing picomoles (10⁻¹² moles) of a specific DNA sequence , known as probes (or reporters ).