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 Course Introduction |
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 Syllabus |
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| Topic 1 |
Learning Objectives |
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Toxicology - Definition |
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Branches of Toxicology |
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 PODCAST |
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| Topic 2 |
Learning Objectives |
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Major Disasters |
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Scientists Associated with Toxicology |
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Incidents of Importance in History of Toxicology |
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Historical Developments |
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PODCAST |
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| Topic 3 |
Learning Objectives |
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Classification of Poisons |
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Guidelines for the Cassification of Poisons Based on the Dose |
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Acute Lethal Doses of Certain Compounds |
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Symbolic Representation of Toxicity of Xenobiotics |
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Types of Poisoning |
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Toxicity Testing |
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Chronicity Factor |
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Untoward Effects due to Poisonous Substances |
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Common Causes of Poisoning |
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PODCAST |
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| Topic 4 |
Learning Objectives |
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Introduction |
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Historical Evidences |
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Clinical Evidences |
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Circumstantial Evidences |
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Pathological Evidences |
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Analytical Evidences |
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Samples to be sent for Analytical Evidences |
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PODCAST |
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| Topic 5 |
Learning Objectives |
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Introduction |
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Toxicant Disposition |
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Absorption and Transport |
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Tissue Distribution |
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Biotransformation |
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Excretion of Xenobiotics |
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PODCAST |
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| Topic 6 |
Learning Objectives |
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Toxicodynamics (Mechanism of Action) |
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Specific Mechanisms of Intoxication |
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 Toxicokinetics and Toxciodynamics |
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Stages of Toxicity Development |
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Action at Delivery Stage |
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Action After Interaction With Target Molecule |
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Cellular Dysfunction and Injury |
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Dysrepair |
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PODCAST |
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| Topic 7 |
Learning Objectives |
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Classification of Factors |
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Toxicant Related Factors |
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Exposure Related Factors |
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Animal Related Factors |
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Environment Related Factors |
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PODCAST |
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| Topic 8 |
Learning Objectives |
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Introduction |
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Removal of the Source of the Poison |
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Delaying Further Absorption with Emetics |
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Gastric Lavage and Other Methods to Delay Absorption |
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Hastening Elimination of the Absorbed Poison |
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Supportive Therapy |
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PODCAST |
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| Topic 9 |
Learning Objectives |
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Antidotes |
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Specific Antidotes |
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Receptor Antagonists |
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Alteration of Drug Metabolism |
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Physiologic Antagonists |
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Chelating Agents |
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PODCAST |
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| Topic 10 |
Learning Objectives |
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Characteristics of Toxic Metals |
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Sources of Arsenic Poisoning |
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Factors Affecting Toxicity |
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Absorption and Fate |
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Mechanism of Toxicity |
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Consequences of Toxicity |
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Clinical Symptoms |
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PM lesions |
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Diagnosis and Treatment |
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PODCAST |
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| Topic 11 |
Learning Objectives |
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Sources of Lead Poisoning |
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Factors Influencing Toxicity |
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Absorption and Fate |
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Mechanism of Toxicity |
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Clinical Symptoms |
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PM Lesions |
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Diagnosis |
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Treatment |
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PODCAST |
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| Topic 12 |
Learning Objectives |
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Sources of Mercury Poisoning |
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Absorption and Fate |
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Mechanism of Toxicity |
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Clinical Symptoms and PM Lesions |
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Diagnosis and Treatment |
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Sources of Iron Poisoning |
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Properties of Toxicological Importance |
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Absorption and Fate |
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Mechanism of Toxicity |
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Pathophysiology of Iron Toxicosis |
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Clinical Symptoms and PM Lesions |
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Treatment |
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PODCAST |
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| Topic 13 |
Learning Objectives |
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Sources of Selenium Poisoning (including plants) |
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Absorption and Fate |
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Mechanisms of Toxicity |
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Clinical Symptoms and PM Lesions |
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Diagnosis and Treatment |
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PODCAST |
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| Topic 14 |
Learning Objectives |
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Sources of Copper Poisoning |
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Absorption and Fate |
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Mechanism of Toxicity |
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Clinical Symptoms and PM Lesions |
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Treatment |
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Sources of Molybdenum Poisoning |
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Factors Affecting Toxicity |
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Absorption and Fate |
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Mechanism of Toxicity |
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Clinical Symptoms |
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Treatment |
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PODCAST |
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| Topic 15 |
Learning Objectives |
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Sources of Nitrite Poisoning |
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Factors Affecting Toxicity |
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Mechanism of Toxicity |
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Clinical Symptoms and PM Lesions |
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Diagnosis and Treatment |
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Sources and Mechanism of Toxicity |
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Clinical Symptoms, Diagnosis and Treatment |
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PODCAST |
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| Topic 16 |
Learning Objectives |
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Sources of Urea Poisoning |
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Properties of Toxicological Importance |
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Absorption and Fate |
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Mechanism of Action |
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Clinical Symptoms and PM Lesions |
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Diagnosis and Treatment |
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PODCAST |
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| Topic 17 |
Learning Objectives |
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Sodium Chloride Poisoning (Salt Poisoning) |
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Mechanism of Toxicity |
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Clinical Symptoms and PM Lesions |
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Diagnosis and Treatment |
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Sources of Fluoride Poisoning (Fluorosis) |
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Absorption and Fate |
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Mechanism of Toxicity |
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Clinical Symptoms and Treatment |
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Carbon Monoxide Poisoning |
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Sulphur Dioxide Poisoning |
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Hyderogen Sulphide Poisoning |
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Nitrogen Dioxide Poisoning |
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PODCAST |
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| Topic 18 |
Learning Objectives |
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Introduction |
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Toxic Principles |
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PODCAST |
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| Topic 19 |
Learning Objectives |
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Atropa belladonna |
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Conium maculatum (Hemlock) |
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Datura stromonium (thorn apple, Jimson weed) |
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Ipomoea species |
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Nerium and Thevetia |
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Solanum |
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Strychnine |
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PODCAST |
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| Topic 20 |
Learning Objectives |
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Sources of Cyanide Poisoning |
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Factors Affecting Toxicity |
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Absorption and Fate |
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Mechanism of Toxicity |
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Clinical Symptoms and PM Lesions |
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Diagnosis |
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Treatment |
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PODCAST |
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| Topic 21 |
Learning Objectives |
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Oxalate containing plants |
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Thiaminase containing plants |
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Thiaminase Induced Toxicity |
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Signs and treatment |
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PODCAST |
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| Topic 22 |
Learning Objectives |
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Cannabis sativa and Cannabis indica |
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Milkweeds (Asclepias) |
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Ricinus communis |
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Abrus precatorius |
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Allium species |
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Calotropis gigantea |
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Gossypium |
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Lathyrus sativum |
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PODCAST |
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| Topic 23 |
Learning Objectives |
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Introduction |
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Classification of photosensitization |
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Primary Photosensitization or Type I |
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Aberrant Endogenopus Pigment Synthesis or Type II |
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Secondary (Hepatogenous) Photosensitization |
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Type IV Photosensitivity |
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Clinical Signs |
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Diagnosis and Treatment |
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Phenothiazine |
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Absorption and Fate |
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Clinical Signs |
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Diagnosis and Treatment |
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Tetradymia - Artemisia Poisoning |
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Tribulus terrestris (Puncture vine) |
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Lantana camara and Lippia spp. |
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Lantana camara - Mechanism of Toxicity |
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Parthenium |
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PODCAST |
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| Topic 24 |
Learning Objectives |
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Mycotoxin |
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Aflatoxin Poisoning |
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Properties of Toxicological Importance |
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Toxicity |
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Toxicokinetics |
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Mechanism of Action |
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Clinical Symptoms and PM Lesions |
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Diagnosis and Treatment |
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Rubratoxins |
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Penicillic Acid |
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PODCAST |
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| Topic 25 |
Learning Objectives |
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Fumonisins |
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Mechanisms of Action |
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Clinical Symptoms |
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PM Lesions, Diagnosis and Treatment |
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Citreoviridin, Patulin and Ochratoxins |
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Zearalenone |
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PODCAST |
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| Topic 26 |
Learning Objectives |
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Types of Bacterial Toxins |
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Factors Causing Bacterial Growth in Foodstuff |
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Toxicokinetics and Mechanism of Action of S. aureus and B. cereus |
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Clinical Symptoms |
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Treatment |
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Botulism |
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Mechanism of Action |
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Clinical signs |
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Treatment |
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Tetanus |
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Mechanism of toxicity |
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Clinical Symptoms |
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Treatment |
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PODCAST |
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| Topic 27 |
Learning Objectives |
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Introduction |
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Organochlorine (Chlorinated hydrocarbon) |
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Absorption and Fate |
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Mechanism of Toxicity |
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Clinical Symptoms and PM Lesions |
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Diagnosis and Treatment |
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PODCAST |
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| Topic 28 |
Learning Objectives |
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Introduction |
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Sources of Organophosphorus Compounds |
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Properties of Toxicological Importance |
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Mechanism of Action |
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Mechanism of Toxicity |
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Clinical Symptoms |
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Treatment |
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Introduction |
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Toxicokinetics |
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Mechanism of Action |
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Clinical Symptoms and Treatment |
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Differences between organophosphosphates and carbamates |
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PODCAST |
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| Topic 29 |
Learning Objectives |
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Sources of Pyrethrins and Pyrethroids |
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Classification |
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Toxicity |
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Toxicokinetics |
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Mechanism of Action |
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Clinical Symptoms and PM Lesions |
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Diagnosis and Treatment |
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Rotenone |
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Amitraz |
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Ivermectin and Milbemycin |
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PODCAST |
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| Topic 30 |
Learning Objectives |
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Introduction |
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Anticoagulant Rodenticieds |
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Factors Enhancing Toxicity |
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Toxicokinetics |
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Mechanism of Toxicity |
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Clinical Symptoms |
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Diagnosis |
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Treatment |
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Alphanaphthyl Thiourea (ANTU) |
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Bromethalin |
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Cholecalciferol |
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Phosphorus |
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Red squill (Urginea maritima) |
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Sodium fluroacetate |
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Strychnine |
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Thallium |
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Zinc phosphide |
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Metaldehyde |
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Herbicides and Fungicides |
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Avicides |
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PODCAST |
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| Topic 31 |
Learning Objectives |
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Zootoxins |
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Snake poisoning |
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Clinical signs, diagnosis, treatment |
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Scorpion poisoning |
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Spider poisoning |
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Wasp sting |
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Toad and poison arrow poisoning |
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Avian poisoning |
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Snail poisoning |
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Fish Poisoning |
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Tick Poisoning |
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PODCAST |
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| Topic 32 |
Learning Objectives |
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Introduction |
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Hazard |
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Risk |
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Risk Assessment |
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Risk Management |
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Residue |
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Importance of Residues |
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Pharmacokinetics and Residues |
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Safety of Veterinary Drugs |
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Formation of Drug Residues |
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Types of Residues |
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Residues of Antibacterial Drugs |
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Consumer Safety |
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Acceptable Daily Intake |
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Withdrawal Time |
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MRL |
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Prevention of Residues |
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Control Systems for Residue Prevention |
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Codex Alimentarius Commission and HACCP |
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PODCAST |
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| Topic 33 |
Learning Objectives |
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Introduction |
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Historical Background |
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UV Rays and Infrared Rays |
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Radiation |
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Radiation Source and Units |
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Radioactive Material |
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Irradiation- Sensitivity, Half life, Exposure, Absorption |
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Industrial Toxicants |
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Occupational Hazards |
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PODCAST |
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| Topic 34 |
Learning Objectives |
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Introduction |
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Classes of Food Additives and Examples |
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Toxicity of Feed Additives |
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Safety of Feed Additives |
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Reasons for Use of Feed Additives in Animal Feed |
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Precautions to be Taken While Using Feed Additives in Animal Feed |
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PODCAST |
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| Topic 35 |
Question Bank |
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Reference and Further Reading |
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Acknowledgement |
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Participants